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Table 2 Proportion of participants who received antiretroviral prescriptions according to age strata (< 50 vs. ≥ 50 years) in a referral center in Rio de Janeiro, Brazil, 2019 (N = 4547)

From: Pharmacotherapeutic profile, polypharmacy and its associated factors in a cohort of people living with HIV in Brazil

 

Total

N = 4547 (%)

< 50 years

N = 2932 (%)

≥ 50 years

N = 1615 (%)

P value

NRTI1

4348 (95.6)

2858 (97.5)

1490 (92.3)

< 0.001

Lamivudine

4337 (95.4)

2853 (97.3)

1484 (91.9)

< 0.001

Tenofovir

3718 (81.8)

2608 (88.9)

1110 (68.7)

< 0.001

Abacavir

343 (7.5)

151 (5.2)

192 (11.9)

< 0.001

Zidovudine

304 (6.7)

122 (4.2)

182 (11.3)

< 0.001

NNRTI1

1638 (36.0)

1067 (36.4)

571 (35.4)

0.49

Efavirenz

1551 (34.1)

1031 (35.2)

520 (32.2)

0.044

Etravirine

59 (1.3)

22 (0.8)

37 (2.3)

< 0.001

Nevirapine

19 (0.4)

10 (0.3)

9 (0.6)

0.28

Rilpivirine

10 (0.2)

5 (0.2)

5 (0.3)

0.34

INSTI

1999 (44.0)

1302 (44.4)

697 (43.2)

0.42

Dolutegravir

1979 (43.5)

1291 (44.0)

688 (42.6)

0.35

Raltegravir

36 (0.8)

23 (0.8)

13 (0.8)

0.94

PI

2023 (44.5)

1112 (37.9)

911 (56.4)

< 0.001

Ritonavir

2023 (44.5)

1112 (37.9)

911 (56.4)

< 0.001

Darunavir

1180 (26.0)

616 (21.0)

564 (34.9)

< 0.001

Atazanavir

909 (20.0)

529 (18.0)

380 (23.5)

< 0.001

Lopinavir

12 (0.3)

6 (0.2)

6 (0.4)

0.29

Tipranavir

6 (0.1)

0 (0)

6 (0.4)

< 0.001

FI

    

Enfurvitide

8 (0.2)

4 (0.1)

4 (0.1)

0.39

CCR5 antagonist

    

Maraviroc

40 (0.9)

13 (0.4)

27 (1.7)

< 0.001

  1. NRTI: nucleoside reverse transcriptase inhibitor; NNRTI: nucleoside/nucleotide reverse transcriptase inhibitors; INSTI: integrase inhibitors; PI: protease inhibitors; FI: fusion inhibitors. 1Tenofovir/Lamivudine/Efavirenz co-formulation was considered to calculate proportion of users