Table 3 Logistic Regression Analysis for Identification of Predictors of kidney disease in PLWH on ART
From: Prevalence and risk factors for kidney disease among hospitalized PLWH in China
Univariate Model Unadjusted OR(95%CI) | P | Multivariate Model Adjusted OR(95%CI) | P | |
|---|---|---|---|---|
Age | 1.048(1.026–1.071) | < 0.001 | 1.034(1.003–1.066) | 0.032 |
Female | 1.545(0.757–3.156) | 0.232 | 0.754(0.256–2.217) | 0.608 |
BMI | 1.010(0.933–1.093) | 0.805 | 1.077(0.965–1.203) | 0.185 |
HBV coinfection | 0.552(0.158–1.934) | 0.353 | 0.567(0.120–2.691) | 0.475 |
HCV coinfection | 1.606(0.538–4.795) | 0.396 | 0.638(0.136–2.985) | 0.568 |
Syphilis | 0.574(0.294–1.119) | 0.103 | 0.394(0.146–1.060) | 0.065 |
Hypertension | 3.451(1.550–7.682) | 0.002 | 1.004(0.276–3.649) | 0.995 |
Diabetes mellitus | 5.240(2.315–11.864) | < 0.001 | 3.271(0.921–11.615) | 0.067 |
Tumor | 0.930(0.361–2.397) | 0.880 | 0.600(0.170–2.109) | 0.425 |
duration of HIV | 1.004(1.000-1.009) | 0.056 | 1.000(0.991–1.009) | 0.923 |
duration of ART | 1.009(1.003–1.016) | 0.007 | 1.015(1.000-1.030) | 0.051 |
HIV viral load | 1.000(1.000–1.000) | 0.705 | 1.000(1.000–1.000) | 0.801 |
≥ 20 copies/mL | 0.690(0.394–1.211) | 0.196 | 0.749(0.299–1.879) | 0.538 |
CD4 count | 1.000(0.999–1.001) | 0.769 | 1.000(0.999–1.001) | 0.945 |
>200 cells/ uL | 1.102(0.639–1.902) | 0.726 | 1.239(0.408–3.761) | 0.706 |
TDF-containing regimen | 1.404(0.730–2.700) | 0.309 | 0.468(0.169–1.296) | 0.144 |
Hb | 0.977(0.967–0.988) | < 0.001 | 0.968(0.948–0.988) | 0.002 |
PCT | 1.198(1.002–1.434) | 0.048 | 1.127(0.919–1.383) | 0.251 |
UA | 1.001(0.999–1.003) | 0.196 | 1.002(1.000-1.004) | 0.081 |
ALB | 0.900(0.857–0.946) | < 0.001 | 0.912(0.834–0.997) | 0.044 |
HCY | 0.993(0.969–1.018) | 0.593 | 0.990(0.958–1.023) | 0.542 |
CRP | 1.006(1.001–1.011) | 0.018 | 1.003(0.994–1.011) | 0.567 |
CHOL | 1.175(0.943–1.463) | 0.151 | 1.633(0.523–5.094) | 0.398 |
TG | 1.076(0.963–1.202) | 0.193 | 1.001(0.727–1.378) | 0.995 |
HDLC | 1.025(0.421–2.495) | 0.957 | 2.496(0.400-15.590) | 0.328 |
LDLC | 1.019(0.727–1.430) | 0.913 | 0.530(0.150–1.882) | 0.326 |