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Table 1 Epidemiological data and pre-IRIS data

From: A case of syphilis associated with immune reconstitution inflammatory syndrome and review of the literature

Author, country, and years of publication

Sex

Age (years)

CDC

Naïve or experienced to ART

HIV viral load (copies/ml) and CD4 + 

count (cells/μl)

Basal treponemal/non treponemal test

Precedent sexual encounters (last six months)

Mitra et al. [3], India, 2021

M

48

C3

Naïve

300,000/20

NR*1/Negative

No

Alcedo et al. [8], Peru, 2019

M

21

A3

Naïve

96,000/91

NR/Negative

Not reported

Yap et al. [7], Australia, 2017

M

71

B3

Naïve

177,828 /185

Negative/Negative

Yes, four weeks ago

Frunza-Stefan et al. [11], China, 2016

M

52

B3

Naïve

280,000 /40

NR/Negative

Yes, six months ago

Braue et al.[4], USA, 2015

M

36

NR

Experienced

NR/324

NR/NR

NR

Khatri et al. [12], USA, 2014

M

43

C3

Experienced

344,000/42

NR/RPR 1:16

No

Vasudevan et al. [9], India, 2013

M

44

C3

Naïve

200,000/92

NR/Negative

Yes, six months ago

Bernal et al. [13], Spain, 2009

M

43

B2

Experienced

31,500/320

NR/Negative

NR

Hardwick et al. [14], England, 2006

M

36

NR

Experienced

NR/NR

Negative /Negative

NR

Moloney et al. [15], Australia, 2004

M

45

A3

Experienced

NR/12

Negative/Negative

Yes

Brochard et al. [16], France, 2017

M

24

C3

Experienced

251,189/31

Negative/Negative

NR

Ceccarelli et al. [17], Italy, 2010

M

28

A3

Naïve

100,000/142

Negative/Negative

NR

Rushing et al. [5], USA, 2008

M

46

C3

Naïve

71,000/8

NR/RPR 1:256

NR

Bucher et al.[6], USA, 2011

M

46

NR

Experienced

25,300/106

Positive/RPR 1:1024

NR

Our case, Italy, 2022

M

42

C3

Experienced

258/196

Negative/Negative

Yes

  1. *1not reported