Fig. 1From: CRISPR/Cas9: a tool to eradicate HIV-1Schematic diagram of HIV-1 provirus gene editing by CRISPR/Cas9. Cas9 protein combined with sgRNAs introduces double-stranded breaks at specific regions. The breaks are repaired by two pathways; NHEJ which incorporates random indel mutations; and Homologous dependent repair (HDR) which introduces specific sequences with the help of donor templatesBack to article page