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Table 2 Univariable and multivariable logistic regression of viral non-suppression in 647 PLHIV on ART in Guatemala

From: Factors associated with viremia in people living with HIV on antiretroviral therapy in Guatemala

Variable

Univariable

Multivariable

aOR

95% CI

p-value

aOR

95% CI

p-value

Smoking

2.06

1.14–3.73

0.017

1.73

0.83–3.60

0.141

Excessive alcohol consumption

1.95

1.03–3.69

0.041

2.56

1.18–5.54

0.017

Perceived difficulty attending healthcare

2.09

1.33–3.29

0.001

2.07

1.25–3.42

0.005

No comorbidities

1.63

1.04–2.56

0.034

1.72

1.04–2.84

0.033

Past AIDS defining illness

2.14

1.36–3.36

0.001

1.23

0.72–2.11

0.450

Low CD4 count at diagnosis

2.55

1.54–4.22

0.000

2.34

1.30–4.20

0.004

Treatment interruption ≥ seven days

4.70

2.41–9.18

0.000

4.51

2.13–9.58

0.000

Multiple prior ART regimens

3.69

2.24–6.09

0.000

2.82

1.59–4.99

0.000

Multiple-daily dosing

2.43

1.53–3.86

0.000

1.59

0.92–2.74

0.095

Sexual orientation

 MSM

1.00

 

0.036

1.00

 

0.064

 Bisexual

3.95

1.4–11.11

0.009

4.04

1.33–12.3

0.014

 Heterosexual

2.40

1.07–5.38

0.033

1.61

0.66–3.91

0.298

Age 50 and below

1.11

0.62–1.98

0.723

   

Male

1.23

0.78–1.93

0.381

   

Not indigenous ethnicity

1.26

0.65–2.47

0.496

   

Primary education or less

1.39

0.88–2.19

0.157

   

Individual income ≤ CBAa

2.00

0.94–4.27

0.074

   

Home owner

1.27

0.78–2.05

0.334

   

Lack of access to basic utilities

1.32

0.69–2.50

0.400

   

Prior illicit drug use

1.58

0.83–3.02

0.168

   

Travel time to healthcare > 1 h

1.27

0.79–2.04

0.330

   

Borrows money for transport to care

1.20

0.75–1.92

0.456

   

Travel cost ≥ $2.6 roundtripb

1.15

0.74–1.81

0.534

   

Integrase inhibitor-based regimen

1.47

0.93–2.32

0.095

   
  1. MSM men who have sex with men, ART antiretroviral therapy, aOR adjusted odds ratio, CI confidence interval
  2. Significant variables (p < 0.05) in univariable analysis were entered into multivariable analysis
  3. aMonthly income ≤ Canasta Básica Alimentaria, the cost to feed an average Guatemalan household per month
  4. b$2.6 was the median cost of transport reported in the cohort