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Table 3 Reasons for ART discontinuation by study period

From: Trends and factors associated with modification or discontinuation of the initial antiretroviral regimen during the first year of treatment in the Turkish HIV-TR Cohort, 2011–2017

Reason for discontinuation

Year of initial ART

2011–2014 n (%)

2015–Feb 2017 n (%)

Total

n (%)

P

Intolerance/toxicity

91 (47.2)

67 (42.4)

158 (45.0)

0.056

Treatment simplification

12 (6.2)

22 (13.9)

34 (9.7)

0.086

Patient’s willingness

16 (8.3)

10 (6.3)

26 (7.4)

0.239

Poor compliance

16 (8.3)

9 (5.7)

25 (7.1)

0.162

Prevention of future toxicities

6 (3.1)

15 (9.5)

21 (6.0)

0.049

Virologic failure

17 (8.8)

2 (1.3)

19 (5.4)

0.001

Clinician’s preference

6 (3.1)

13 (8.2)

19 (5.4)

0.108

Others

29 (15.0)

20 (12.7)

49 (14.0)

0.199

Total

193 (100)

158 (100)

351 (100)

 
  1. p by Chi square