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Table 2 Univariate and multivariate analysis of predictors of immunologic failure

From: Predictors of first-line antiretroviral therapy failure among adults and adolescents living with HIV/AIDS in a large prevention and treatment program in Nigeria

Characteristics

Unadjusted

RR PR (95% CI)

p-value1

Adjusted

PRR (95% CI)

p-value2

Gender

 Male

1.00

 

1.00

 

 Female

0.98 (0.88–1.09)

0.17

1.22 (1.07–1.40)

0.005

Occupation

 Employed

0.92 (0.80–1.05)

0.19

1.18 (0.95–1.46)

0.14

 Others

1.00

 

1.00

 

Service entry point

 Voluntary counseling and testing

0.78 (0.70–0.88)

< 0.001

0.79 (0.64–0.91)

0.002

 Others

1.00

 

1.00

 

NVP containing regimen

 Yes

1.35 (1.18–1.54)

< 0.001

1.21 (0.99–1.45)

0.23

 No

1.00

 

1.00

 

WHO stage

 1 or 2

1.00

0.14

1.00

0.013

 3 or 4

0.97 (0.84–1.19)

 

0.76 (0.60–0.96)

 

CD4 cell count, cells/mm3

 200 +

0.22 (0.20–0.24)

 

0.19 (0.16–0.22)

 

 < 200

1.00

< 0.001

1.00

< 0.001

  1. 1Prevalence RatioRelative risk (PRRR), 95% confidence interval (CI) and p-values were calculated using log binomial regression
  2. 2Multivariate models included all predictors significant at p value < 0.20