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Table 4 HIVDR mutations by treatment status among 16 FSW with detectable HIVDR in Guinea-Bissau

From: The HIV care continuum and HIV-1 drug resistance among female sex workers: a key population in Guinea-Bissau

Drug class

HIVDR Mutation (n = 16)

Treatment Naive (n = 5)

ART experienceda (n = 11)

Total (n = 16)

NNRTI

K103N/S

3 (60.0%)

4 (36.4%)

7 (43.8%)b

 

A98G

0 (0.0%)

2 (18.2%)

2 (12.5%)

 

E1238A

0 (0.0%).

1 (9.1%)

1 (6.3%)

 

K238N

0 (0.0%)

1 (9.1%)

1 (6.35)

 

K238T

0 (0.0%)

1 (9.1%)

1 (6.3%)

 

P225H

0 (0.0%)

1 (9.1%)

1 (6.3%)

 

V106A

0 (0.0%)

1 (9.1%)

1 (6.3%)

 

V179E

0 (0.0%)

1 (9.1%)

1 (6.3%)

 

Y188H

0 (0.0%)

1 (9.1%)

1 (6.3%)

 

Y188L

1 (20.0%)

0 (0.0%)

1 (6.3%)

NRTI

M184V

0 (0.0%)

6 (54.5%)

6 (37.5%)b

 

M41L

1 (20.0%)

1 (9.1%)

2 (12.5%)

 

T215Y

0 (0.0%)

2 (18.2%)

2 (12.5%)

 

D67N

1 (20.0%)

0 (0.0%)

1 (6.3%)

 

E44D

0 (0.0%)

1 (10.0%)

1 (6.3%)

 

K219E

1 (20.0%)

0 (0.0%)

1 (6.3%)

 

T215FY

0 (0.0%)

1 (9.1%)

1 (6.3%)

 

T215I

1 (20.0%)

0 (0.0%)

1 (6.3%)

PI

L89V

0 (0.0%)

1 (9.1%)

1 (6.3%)b

  1. Data are n (%)
  2. ART antiretroviral therapy, HIVDR HIV-1 drug resistance, NNRTI non-nucleoside reverse transcriptase inhibitors, NRTI nucleoside reverse transcriptase inhibitor, PI protease inhibitors
  3. aIncluding 10 study participants with current ART use and 1 study participant with previous ART use
  4. bThe most common HIVDR in each drug class highlighted in italics