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Table 2 Univariate regression of potential predictors of the change in eGFR in patients switched from TDF to TAF

From: Renal function change after switching tenofovir disoproxil fumarate for tenofovir alafenamide in the HIV-positive patients of a metropolitan sexual health service

Variable

Coefficient (95% CI)

p value

Age

0.120 (− 0.080 to 0.396)

0.189

Cumulative TDF exposure

0.025 (− 0.069 to 0.031)

0.454

Pre-switch eGFR

− 0.381 (− 0.516 to − 0.247)

< 0.001

Pre-switch uPCR

0.085 (− 0.194 to 0.153)

0.814

  1. Statistically significant p value is in italic
  2. eGFR estimated glomerular filtration rate, TAF tenofovir alafenamide, TDF tenofovir disoproxil fumarate
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AIDS Research and Therapy

ISSN: 1742-6405

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