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Table 1 Summary of diagnostic test results and proposed mechanisms of false positivity

From: Spectrum of false positivity for the fourth generation human immunodeficiency virus diagnostic tests

 

Abbott p24 antigen/antibody

MultiSpot HIV-1/HIV-2 differentiation

HIV proviral DNA

HIV RNA viral load

Alternative diagnosis/mechanism of false positivity

Other explanatory studies/reports

Case 1

Positive

Non-reactive

Not done

Negative

EBV infection and reactive lymphocytosis

[7–13]

Case 2 patient

Positive

Reactive to HIV-1

Negative

Negative

Metastatic cancer

[18]

Case 2 exposed health care provider

Positive

Reactive to HIV-1

Negative

Negative

Healthy/query poor specificity of individual test kit

[16]

Case 2 exposed health care provider (6 month follow up)

Negative

 

Negative

Negative

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