Skip to main content

Table 3 Validity and predictive value between CD4 count and TLC among HIV infected patients in different age categories at Gondar University Hospital, 2011

From: Total Lymphocyte Count as surrogate marker for CD4 Cell Count in HIV-Infected Individuals in Gondar University Hospital, Northwest Ethiopia

Age Marker N P SE SP PPV NPV Kappa P - value
In all age group CD4 count ≤ 200 cell/μL 143 35.8 100 100 100 100 0.24 0.001
TLC ≤ 1200 cell/μL 59 14.8 32.86 95.33 79.66 71.85
18-29 CD4 count ≤ 200 cell/μL 36 9.0 100 100 100 100   
TLC ≤ 1200 cell/μL 12 3.0 22.22 95.65 66.66 75.86 0.22 0.002
30-39 CD4 count ≤ 200 cell/μL 66 16.5 100 100 100 100   
TLC ≤ 1200 cell/μL 33 8.2 39.39 92.92 78.78 69.69 0.35 0.000
40-49 CD4 count ≤ 200 cell/μL 26 6.5 100 100 100 100   
TLC ≤ 1200 cell/μL 12 3.0 26.92 90.74 58.33 72.05 0.20 0.038
50 & above CD4 count ≤ 200 cell/μL 16 4.0 100 100 100 100   
  TLC ≤ 1200 cell/μL 7 1.8 43.75 100 100 55 0.38 0.011
  1. Abbreviation: N, number; P, Prevalence (%); SE, Sensitivity (%); SP, Specificity (%); PPV, Positive predictive value; NPV, Negative predictive value; CD4, T-lymphocyte CD4 positive; TLC, Total lymphocyte count; HIV, Human Immunodeficiency virus.