Table 3 Comparisons of clinical parameters to determine risk factors of immunological failure among 535 HIV-infected patients
Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
Odds Ratio (95% CI) | P-value | Odds Ratio (95% CI) | P-value | |
Male vs. female | 1.67 (1.16-2.40) | 0.006 | ||
Age < 40 vs. ≥ 40 years | 0.92 (0.65-1.32) | 0.667 | - | - |
Heterosexual vs. non-heterosexual transmission | 5.14 (0.65-40.50) | 0.120 | - | - |
Urban vs. rural area | 0.86 (0.57-1.31) | 0.492 | - | - |
No health insurance vs. had health insurance | 0.73 (0.23-2.33) | 0.597 | - | - |
OIs before cART vs. no OIs before cART | 1.49 (1.03-2.15) | 0.032 | - | - |
Baseline CD4 cell count < 100 vs. ≥ 100 cells/mm 3 | 2.74 (1.81-4.15) | < 0.001 | 2.69 (1.73-4.18) | < 0.001 |
CD4 cell increase of < 50 vs. ≥ 50 cells/mm3 after 6 months of cART | 2.21 (1.44-3.39) | < 0.001 | 2.39 (1.54-3.73) | < 0.001 |
Positive HCV antibody vs. negative HCV antibody | 1.823 (1.015-3.30) | 0.048 | - | - |
Positive HBs Ag vs. negative HBs Ag | 1.30 (0.67-2.51) | 0.434 | - | - |
Adherence rate < 95% vs. ≥ 95% | 2.87 (0.26-32.1) | 0.392 | - | - |