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Table 1 CCR5 and CD45 genotypes in exposed uninfected subjects (ESN), HIV-1 seropositive patients and general population control groups.

From: Partial protective effect of CCR5-Delta 32 heterozygosity in a cohort of heterosexual Italian HIV-1 exposed uninfected individuals

Genotype ESN (%) (n = 30) HIV-1 seropositive (%) (n = 120) Pc General Population (%) (n = 120) Pd
CCR5a wt/wt 24 (80) 111 (92.5) 0.04 108 (90) ns
  Δ32/wt 6 (20) 9 (7.5) 0.04 12 (10) ns
  Δ32/Δ32 0 (0) 0 (0) ns 0 (0) ns
CD45b Wt/wt 29 (97) 117 (97.5) ns 117 (97.5) ns
  C77G/wt 1 (3) 3 (2.5) ns 3 (2.5) ns
  C77G/C77G 0 (0) 0 (0) ns 0 (0) ns
  1. a WT/WT, homozygous wild type CCR5 genotype; Delta32/Delta32 for homozygous mutant for 32-bp deletion in CCR5 gene and Delta32/wt for heterozygous.
  2. b WT/WT, homozygous wild type CD45 genotype; C77G/C77G for homozygous mutant for the point mutation in exon 4 of CD45 gene and C77G/wt for heterozygous.
  3. c P value calculated comparing ESN individuals vs HIV-1 seropositive control group; p = ns, non significant.
  4. d P value calculated comparing ESN individuals vs General Population control group; p = ns, non significant.