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Table 4 Correlated mutations in standard genotype sequencing dataset

From: The development of drug resistance mutations K103N Y181C and G190A in long term Nevirapine-containing antiviral therapy

 

Position1

Mutation type

Position2

Ckaks

Lod

ART for 12 months

K103N

NRTI

M41L

1.5

7.05

 

NNRTI

Y181C

1.29

5.17

 

G190A

1.6

5.22

 

H221Y

5

2.87

Y181C

NRTI

None

None

None

 

NNRTI

H221Y

6

3.45

G190A

NRTI

None

None

None

 

NNRTI

K103S

3

Inf

ART for over 60 months

K103N

NRTI

T69N

1.33

2.39

 

K70R

1.17

3.32

 

NNRTI

Y181C

1.27

7.16

 

H221Y

2.75

5.5

Y181C

NRTI

D67N

1.8

3.77

 

T69N

2.5

5.85

 

K70R

5

4.95

 

NNRTI

K103N

2

15.78

 

H221Y

4

6.05

G190A

NRTI

D67N

4.8

3.52

 

T69N

4

5.71

 

K70R

3

3.52

 

NNRTI

K101E

6

3.52

 

Y181C

1.5

4.11

 

K103S

10

Inf