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Table 3 Thermal stability of CSIC in CSIC SEF

From: The utility of self-emulsifying oil formulation to improve the poor solubility of the anti HIV drug CSIC

 

Amount of CSIC remaining (mg)

FC1

Week 0

Week 2

Week 3

Week 4

  

25°C

40°C

50°C

25°C

40°C

50°C

25°C

40°C

50°C

A

0.47

0.40 ± 0.01

0.45 ± 0.002

0.48 ± 0.02

0.36 ± 0.001

0.37 ± 0.01

0.39 ± 0.03

0.39 ± 0.04

0.47 ± 0.01

0.49 ± 0.03

B

0.44

0.40 ± 0.008

0.45 ± 0

0.50 ± 0.1

0.35 ± 0.01

0.37 ± 0.02

0.40 ± 0.01

0.39 ± 0.02

0.47 ± 0.02

0.47 ± 0.02

C

0.45

0.414 ± 0.001

0.50 ± 0.01

0.50 ± 0.1

0.36 ± 0

0.39 ± 0.01

0.38 ± 0.02

0.40 ± 0.003

0.48 ± 0.003

0.46 ± 0.02

D

0.45

0.42 ± 0.004

0.45 ± 0.01

0.46 ± 0.01

0.34 ± 0.02

0.39 ± 0.02

0.4 ± 0.01

0.42 ± 0.004

0.46 ± 0.01

0.50 ± 0.001

E

0.42

0.39 ± 0.001

0.44 ± 0.04

0.43 ± 0.01

0.34 ± 0.01

0.36 ± 0.01

0.38 ± 0.01

0.39 ± 0.001

0.44 ± 0.002

0.47 ± 0.005

  1. 1 = Formulation code.